The "9-channel fluorescence microscopy workstation" of Nanjing Kanshijie Intelligent Technology is about to be released


 360screenshot20250905131523851.jpg

According to Pan Feng, CEO of Nanjing Kanshijie Intelligent Technology, after more than a year of intensive research and development, the 9-channel real-time multi-spectral fluorescence microscope workstation will be globally launched in December of this year.

 

360screenshot20250905131530106.jpg

(Dual-band fluorescence microscopy workstation) 

 

This product combines the advantages of wide-field fluorescence microscopy and confocal microscopy, allowing large-field high-speed imaging and simultaneous acquisition of multi-spectral channels. The imaging speed depends only on the camera frame rate, which is much higher than that of confocal microscopy. 

The "Multi-Spectral Fluorescence Microscopy Workstation" uses the team-developed spectral chip to simultaneously acquire real-time data from 9 spectral channels on an inverted fluorescence microscope, combined with a non-linear spectral unmixing algorithm, to achieve high-speed fluorescence microscopy and classification of multiple colors. 

At present, the fluorescence target recording bio-microscope in real time is a breakthrough technology. This will fill the blank in the field of multi-fluorescence real-time monitoring, especially with advantages in the following applications: 

Multifactorial cell dynamics research

Can be used for intercellular communication, metabolic pathway analysis 

Drug development

Real-time observation of the mechanism of action of multi-target drugs 

Neuroscience and Brain-Computer Interface Research

 Record multiple神经 markers signals 

The current state of multi-fluorescence technology development worldwide 

Mainstream technology platform:

  • Multi-channel confocal microscopes (such as products from Zeiss, Leica, Nikon, etc.) can achieve imaging of multiple fluorescence channels, but they are usually scanned layer by layer, expensive and have low real-time performance.

 

  • Spectral Imaging: Based on spectral resolution technology, it can record multiple fluorescence channels, but most of the equipment still relies on spectral deconvolution, and the speed is limited.

 

  • Wide-field fluorescence microscopy combined with CMOS camera is low cost and can record faster, but resolution and background light interference are limiting factors.

 

Compared with current mainstream commercial products, the microscopes workstation launched by the Kexi界 team can significantly improve the number of targets observed and the dynamic monitoring capability. Moreover, due to the use of advanced high-spectral chip integration technology, it has a strong comparative advantage in cost control and has great market potential in cutting-edge biomedical research. 

View the horizon intelligent technology

Leading technology in hyperspectral imaging

01 

Nanjing KanshiJie Intelligent Technology Co., Ltd., originating from the research and development team of the University of California, has more than ten years of accumulation of spectral chip technology, which has achieved a leading position in the global industry in the field of hyperspectral imaging. It has also received the high honor of "National Key Research and Development Program - Disruptive Technology Innovation Major Special Program" from the Ministry of Science and Technology of China.

This hard-core strength stems from a technical team led by academicians of the Chinese Academy of Sciences and the Chinese Academy of Engineering, who have long been committed to the organic transformation of advanced scientific research achievements into mature industries and have achieved great success.

These factors determine that the series of high-spectral products released by Nanjing Kanshijie Intelligent Technology Co., Ltd. has great market value. 

View the Smart Technology of the horizons

Leading technology in hyperspectral imaging

Innovative design of micro-nano three-dimensional filter structure

Through the engineering of micro-nano optical, the innovative implementation of the filter bank unit three-dimensional matrix eliminates the phenomenon of signal crosstalk between units. The implementation of single-pixel channel multi-band modulation is realized while ensuring high spectral resolution and high spatial resolution.

Advanced composite imaging array design and processing

By fully controlling the light field, the imaging system is endowed with unique light field modulation capability. Combined with advanced optical design, material matching and integrated nano-molding process, the production of high yield and high imaging quality of composite array optical chips is realized.

Leading neural network learning algorithm for spectral recovery

It breaks the pain point that a single pixel in the mainstream mosaic narrowband filtering can only correspond to one spectral channel, and it takes into account both high spatial and spectral resolution, achieving a spectral resolution accuracy of several nanometers.

Multi-spectral fluorescence microscopy workstation

Technical features and advantages

02 

Nanjing Kanshijie Intelligent Technology is about to release a multi-spectral fluorescence microscope workstation with world-leading technology, and there are no direct competitors in the market yet.

The characteristics of the multi-spectral fluorescence microscopy workstation 

High speed: Snapshot imaging, no moving mechanical/electronic components

High compatibility: Adapt to the structure of general microscopes without changing the original imaging field of view.

Compatible with universal sensors: configure 4MP sCMOS camera. Upgradable to EMCCD or 20MP CMOS.

High resolution: 1024*1024 image resolution

Scalability: It can be upgraded from the existing wide-field fluorescence microscopy platform, reducing the cost of ownership. 

This "Multi-spectral Fluorescence Microscopy Workstation" also has the characteristics of being lightweight, easy to operate, and supporting customized development, and has broad application prospects in the future.

For more details on the parameters of the hyperspectral series products, test data, and release information, please follow this official account.